Bio-19: Excretory Products and their Elimination30 Questions
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1. Which of the following nitrogenous wastes is the most toxic and requires large amounts of water for its elimination?
A. Ammonia
B. Urea
C. Uric acid
D. Creatinine
Answer: A. Ammonia
Explanation: Ammonia is the most toxic form of nitrogenous waste and needs a large quantity of water for its removal (ammonotelism).
2. Reptiles, birds, land snails, and insects excrete nitrogenous wastes mainly as:
A. Uric acid
B. Urea
C. Ammonia
D. Amino acids
Answer: A. Uric acid
Explanation: Uricotelic animals excrete uric acid in the form of pellet or paste with a minimum loss of water.
3. What are the excretory structures found in platyhelminthes (e.g., Planaria)?
A. Flame cells (Protonephridia)
B. Nephridia
C. Malpighian tubules
D. Antennal glands
Answer: A. Flame cells (Protonephridia)
Explanation: Protonephridia or flame cells are the excretory structures in Platyhelminthes, rotifers, and some annelids.
4. Antennal glands or green glands perform the excretory function in:
A. Crustaceans (e.g., Prawns)
B. Insects (e.g., Cockroach)
C. Annelids (e.g., Earthworm)
D. Molluscs
Answer: A. Crustaceans (e.g., Prawns)
Explanation: Antennal glands or green glands serve as the excretory organs in crustaceans like prawns.
5. On average, how much urea is excreted out by a human adult per day?
A. 25–30 grams
B. 5–10 grams
C. 50–60 grams
D. 100 grams
Answer: A. 25–30 grams
Explanation: An adult human excretes on average 25 to 30 grams of urea per day through urine.
6. Functional unit of the human kidney is called:
A. Nephron
B. Neuron
C. Glomerulus
D. Henle's loop
Answer: A. Nephron
Explanation: Each human kidney contains complex tubular structures called nephrons, which are the functional units.
7. A Malpighian body or renal corpuscle consists of:
A. Glomerulus and Bowman's capsule
B. Glomerulus and PCT
C. Bowman's capsule and Loop of Henle
D. DCT and Collecting duct
Answer: A. Glomerulus and Bowman's capsule
Explanation: Glomerulus along with Bowman's capsule is called the Malpighian body or renal corpuscle.
8. Epithelial cells of Bowman's capsule called podocytes leave intricate spaces called filtration slits in the:
A. Visceral layer of Bowman's capsule
B. Parietal layer of Bowman's capsule
C. Endothelium of glomerular blood vessels
D. Basement membrane
Answer: A. Visceral layer of Bowman's capsule
Explanation: Podocytes are arranged in an intricate manner on the visceral layer of Bowman's capsule, leaving slit pores or filtration slits.
9. Normal Glomerular Filtration Rate (GFR) in a healthy individual is approximately:
A. 125 mL/minute (180 Litres/day)
B. 180 mL/minute
C. 125 Litres/day
D. 50 mL/minute
Answer: A. 125 mL/minute (180 Litres/day)
Explanation: The GFR in a healthy adult is about 125 mL/min, which amounts to 180 Litres of filtrate per day.
10. Juxtaglomerular Apparatus (JGA) releases which hormone in response to a fall in GFR?
A. Renin
B. Rennet
C. Erythropoietin
D. Aldosterone
Answer: A. Renin
Explanation: A drop in glomerular blood flow/GFR activates JG cells to release renin, which converts angiotensinogen to angiotensin I.
11. Maximum reabsorption of water, electrolytes, and essential nutrients occurs in which part of the nephron?
A. Proximal Convoluted Tubule (PCT)
B. Distal Convoluted Tubule (DCT)
C. Descending limb of Loop of Henle
D. Collecting duct
Answer: A. Proximal Convoluted Tubule (PCT)
Explanation: Nearly 70–80% of electrolytes and water, and almost all essential nutrients are reabsorbed by PCT.
12. The descending limb of Loop of Henle is:
A. Permeable to water but almost impermeable to electrolytes
B. Impermeable to water but permeable to electrolytes
C. Impermeable to both water and electrolytes
D. Permeable to electrolytes only
Answer: A. Permeable to water but almost impermeable to electrolytes
Explanation: Descending limb is permeable to water and impermeable to electrolytes, concentrating the filtrate as it moves down.
13. The ascending limb of Loop of Henle is:
A. Impermeable to water but allows transport of electrolytes
B. Permeable to water only
C. Permeable to water and electrolytes equally
D. Impermeable to both water and salts
Answer: A. Impermeable to water but allows transport of electrolytes
Explanation: Ascending limb is impermeable to water, so filtrate gets diluted as electrolytes are reabsorbed actively or passively.
14. Anti-Diuretic Hormone (ADH) or Vasopressin acts mainly on DCT and collecting duct to cause:
A. Increased reabsorption of water, producing concentrated urine
B. Decreased reabsorption of water, producing dilute urine
C. Increased excretion of Na+ ions
D. Inhibition of renin secretion
Answer: A. Increased reabsorption of water, producing concentrated urine
Explanation: ADH facilitates water reabsorption from distal parts of the tubule, preventing diuresis and producing concentrated urine.
15. Atrial Natriuretic Factor (ANF) is secreted by heart atria when blood pressure increases, causing:
A. Vasodilation and decrease in blood pressure
B. Vasoconstriction and increase in blood pressure
C. Secretion of renin and aldosterone
D. Increased water reabsorption in PCT
Answer: A. Vasodilation and decrease in blood pressure
Explanation: ANF acts as a check on the renin-angiotensin mechanism; it causes vasodilation and lowers blood pressure.
16. The mechanism that maintains a high concentration gradient in the renal medullary interstitium is:
A. Counter-current mechanism of Henle's loop and vasa recta
B. Active transport in PCT
C. Ultrafiltration in glomerulus
D. Micturition reflex
Answer: A. Counter-current mechanism of Henle's loop and vasa recta
Explanation: The counter-current flow of filtrate in Henle's loop and blood flow in vasa recta creates an osmotic gradient in the medullary interstitium (300 to 1200 mOsmolL-1).
17. The process of release of urine from the urinary bladder is called:
A. Micturition
B. Hemodialysis
C. Ultrafiltration
D. Exudation
Answer: A. Micturition
Explanation: The neural mechanism causing emptying of the urinary bladder is called the micturition reflex, and the act is micturition.
18. Accumulation of urea in blood due to kidney failure is known as:
A. Uremia
B. Anuria
C. Glycosuria
D. Ketonuria
Answer: A. Uremia
Explanation: Malfunctioning of kidneys leads to buildup of urea in blood, a condition called uremia, which can lead to kidney failure.
19. Presence of glucose (Glycosuria) and ketone bodies (Ketonuria) in urine is an indicator of:
A. Diabetes mellitus
B. Diabetes insipidus
C. Bright's disease
D. Glomerulonephritis
Answer: A. Diabetes mellitus
Explanation: Presence of glucose (glycosuria) and ketone bodies (ketonuria) in urine are indicative of Diabetes mellitus.
20. In insoluble mass of crystallized salts (e.g., oxalates) formed within the kidney is termed:
A. Renal calculi (Kidney stone)
B. Glomerulonephritis
C. Uremia
D. Cystitis
Answer: A. Renal calculi (Kidney stone)
Explanation: Stone or insoluble mass of crystallized salts formed within the kidney is called renal calculus.
21. Inflammation of glomeruli of kidneys is called:
A. Glomerulonephritis
B. Renal calculi
C. Uremia
D. Gout
Answer: A. Glomerulonephritis
Explanation: Glomerulonephritis refers to the inflammation of the renal glomeruli of the kidney.
22. Human kidneys are located between the levels of:
A. Last thoracic and third lumbar vertebra
B. 1st thoracic and 5th lumbar vertebra
C. 12th thoracic and 1st lumbar vertebra
D. 5th thoracic and 12th thoracic vertebra
Answer: A. Last thoracic and third lumbar vertebra
Explanation: Kidneys are reddish-brown, bean-shaped structures situated between the levels of last thoracic (T12) and third lumbar (L3) vertebrae.
23. Cortical nephrons differ from juxtamedullary nephrons because cortical nephrons have:
A. Short Loop of Henle extending only little into medulla
B. Long Loop of Henle running deep into medulla
C. Well developed vasa recta
D. Absence of glomerulus
Answer: A. Short Loop of Henle extending only little into medulla
Explanation: In majority of nephrons (cortical nephrons), loop of Henle is short and extends only very little into medulla, and vasa recta is reduced or absent.
24. Blood vessel that enters the glomerulus is called:
A. Afferent arteriole
B. Efferent arteriole
C. Renal vein
D. Vasa recta
Answer: A. Afferent arteriole
Explanation: Afferent arteriole (a fine branch of renal artery) carries blood into the glomerulus, while efferent arteriole carries blood away.
25. Which of the following is NOT normally filtered into Bowman's capsule during ultrafiltration?
A. Plasma proteins
B. Glucose
C. Amino acids
D. Urea
Answer: A. Plasma proteins
Explanation: Ultrafiltration filters almost all components of blood plasma except proteins into the lumen of Bowman's capsule.
26. Aldosterone causes reabsorption of Na+ and water from which region of the nephron?
A. Distal Convoluted Tubule (DCT)
B. Proximal Convoluted Tubule (PCT)
C. Descending Henle's loop
D. Glomerulus
Answer: A. Distal Convoluted Tubule (DCT)
Explanation: Angiotensin II stimulates adrenal cortex to secrete aldosterone, which causes reabsorption of Na+ and water from distal parts of the tubule (DCT).
27. Which accessory organ aids in excretion by removing sterols, hydrocarbons, and waxes through sebum?
A. Sebaceous glands
B. Sweat glands
C. Liver
D. Lungs
Answer: A. Sebaceous glands
Explanation: Sebaceous glands eliminate sterols, hydrocarbons, and waxes through sebum.
28. Human urine is normally slightly acidic with an average pH of:
A. 6.0
B. 7.4
C. 4.5
D. 8.2
Answer: A. 6.0
Explanation: Human urine is slightly acidic with a characteristic pH averaging around 6.0.
29. What percentage of blood pumped by each ventricle of heart is filtered by kidneys per minute?
A. 20–25% (about 1100–1200 mL)
B. 50%
C. 5–10%
D. 70%
Answer: A. 20–25% (about 1100–1200 mL)
Explanation: On average, 1100–1200 mL of blood is filtered by the kidneys per minute, which constitutes roughly 1/5th (20–25%) of cardiac output.
30. During hemodialysis, which anticoagulant is added to blood drawn from the patient before pumping into the dialyzing unit?
A. Heparin
B. Anti-heparin
C. Histamine
D. Thrombin
Answer: A. Heparin
Explanation: Blood drained from a convenient artery is mixed with an anticoagulant like heparin before passing through a dialyzer.
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